In an effort to revive the wicked mammoth, the colossal biological cases created a woolen mouse

Colossal biological activities, known for its fixed purpose to resurrect the worst mammoth until 2028, claims constant progress. This is proof: genetically engineering mice have a mammoth -like coat.

To inject the woolen mouse, the company scientists found mammoth gene mice versions and then used CRISPR to edit mice embryos, Dr. Beth Shapiro, CEO at Colossal, Techcrunch told Techcrunch. Then these embryos were implanted in the surrogate mouse mothers.

The company says that the coat of wool mice is color, texture and thickness that resemble the features of a mammoth.

Colossal Biosciences believe that the woolly coating will allow its genetic engineering mice to survive in a cold climate. However, the company must first receive approval from The Institutional Committee for the Care and Use of Animals (Iacuc), which provides ethical and humane animal studies before conducting such experiments.

Shapiro said the company should test the cold tolerance of engineering mice to validate if these genes would improve the adaptation of a mammoth to a cold environment.

The Mammoth Return’s Collosal approach includes Mapping the whole genome of extinct woolen mammoth And he compares it to his closest life, the Asian elephant.

Investors were impressed with the speed with which the company creates technology, said Ben Lam, co -founder and CEO of Colossal Biosciences, told TechCrunch when the company announced a A round of $ 200 million in a $ 10.2 billion estimate In January.

In addition to working on a wool mammoth, the company aims to return the Tasmanian tiger and the Dodo bird.

But this goal in 2028 may not be realistic. According to David Gold, Professor of Paleobiology at UC Davis, the creation of multiple mutations in mice is difficult, but not as difficult as the creation of a wool mammoth.

“It is exciting to see mice produce a mammoth -like coat. But there are hundreds of differences between an elephant and mammoth DNA, so there’s a long way, “Gold said. He added that while he believes it would be possible to re -create a wool mammoth, many technical obstacles are ahead.

However, Lam calls the creation of a colosion of the woolen mouse “The Mink of Confusion” for the mission to deactivate the company.

“The animals were born healthy and they had the exact phenotypes we predicted,” Lam said. “The only thing that was unforeseen was the focus of delight. They are just more sweet than we expected. “